Treatment guide · Skin Boosters

Polynucleotide (PN) Injections in Seoul

DNA-fragment skin boosters that help repair thin, damaged or scarred skin over a few sessions.

Ask the clinic for: PN 주사 (폴리뉴클레오티드 주사)

Polynucleotide (PN) Injections explained

PN injections are a group of skin boosters made from polynucleotides, which are purified DNA fragments. Rejuran is the best-known Korean brand, and there are many other Korean and Italian brands. They are used for skin quality, fine lines, acne scars and the under-eye area.

How Polynucleotide (PN) Injections works

The PN gel is injected into the dermis as many small drops. Polynucleotides hold water and are thought to support fibroblasts and calm inflammation, which helps the skin repair itself. Over weeks, skin can look thicker, smoother and more even. Some clinics also apply PN after microneedling or laser.

Who Polynucleotide (PN) Injections is for

• Thin, sensitive or damaged skin
• Fine lines and loss of elasticity
• Shallow acne scars and enlarged pores
• Under-eye crepiness
• Recovery after laser treatments

Who should avoid Polynucleotide (PN) Injections

• People with a fish allergy
• Pregnant or breastfeeding women
• Active infection, acne flares or rash at the site
• Anyone wanting volume or lifting

What happens at the appointment

1. Consultation and choice of brand and area
2. Cleansing and numbing cream for 20–40 minutes
3. Small injections by hand or multi-needle device
4. Soothing mask or cool pack
5. Aftercare and session scheduling

Aftercare and flying home

• Avoid makeup for 12–24 hours
• Avoid saunas, alcohol and hard exercise for 1–2 days
• Do not rub or massage the area for a few days
• Use gentle skincare and sunscreen

Side effects and risks

• Small bumps for 1–2 days
• Redness and pinpoint bruises
• Swelling, especially under the eyes
• Rarely, allergic reaction or infection

How much does Polynucleotide (PN) Injections cost in Seoul?

₩150,000–₩500,000 (about US$110–375) — Price in Seoul depends on the brand (Korean brands are cheaper than imported ones), the amount in cc and the area. Under-eye and full-face treatments are priced differently. Prices are estimates and change with promotions.

Why get Polynucleotide (PN) Injections in Korea?

PN boosters are among the most common skin treatments in Seoul, and several are made by Korean companies. This means wide choice, experienced injectors and lower prices than in many countries.

Frequently asked questions

How much do PN injections cost in Seoul?

PN injections usually cost about ₩150,000–₩500,000 per session in Seoul. The brand and amount used make the biggest difference.

Do PN injections hurt?

They sting more than some boosters because of the many small injections. Numbing cream is applied for 20–40 minutes first.

How many PN sessions do I need?

Most people need about 3 sessions 2–4 weeks apart. Results usually last 4–6 months.

Can I fly after PN injections?

Yes, flying is fine. Small bumps may stay visible for 1–2 days.

Are PN injections safe?

They are generally low risk when done by a doctor. Tell the clinic about any fish allergy, as most PN products come from fish.

Is PN the same as Rejuran?

Rejuran is one brand of PN injection. Other brands use similar polynucleotides but may differ in concentration and price.

Where to get it in Seoul

Foreigner-friendly clinics cluster around Gangnam, Sinsa–Apgujeong–Cheongdam and Myeongdong. Tap a number to zoom in, then tap a pin to ask the clinic on WhatsApp whether they offer this treatment and for a quote.