Treatment guide · Skin Boosters

Plinest in Seoul

An Italian polynucleotide skin booster for repair, elasticity and finer skin texture.

Ask the clinic for: 플리네스트 (PN 스킨부스터)

Plinest explained

Plinest is a skin booster made in Italy from purified polynucleotides (DNA fragments). It belongs to the same family as Rejuran but is a different brand. Clinics use it for fine lines, crepey skin and an uneven texture.

How Plinest works

The polynucleotides are injected into the dermis as small drops with a needle or multi-needle device. They hold water and are thought to support fibroblasts, the cells that make collagen and elastin. This helps the skin become thicker, smoother and more elastic over several weeks. A separate eye version is used for the thin skin under the eyes.

Who Plinest is for

• Fine lines and crepey skin
• Dull or tired-looking skin
• Thin skin under the eyes (eye-specific version)
• Skin recovering after laser treatments
• People who want improvement without volume

Who should avoid Plinest

• Pregnant or breastfeeding women
• People with a fish or salmon allergy, since polynucleotides are often fish-derived
• Active acne, rash or infection in the area
• Anyone wanting lifting or volume

What happens at the appointment

1. Consultation and skin check
2. Cleansing and numbing cream for 20–30 minutes
3. Small injections across the treatment area
4. Soothing mask or cool pack
5. Aftercare advice and next session timing

Aftercare and flying home

• Avoid makeup for 12–24 hours
• Avoid saunas, alcohol and hard exercise for 1–2 days
• Do not rub or massage the area for a few days
• Use sunscreen and gentle skincare

Side effects and risks

• Small bumps that settle in 1–2 days
• Redness and tiny bruises
• Mild swelling, especially under the eyes
• Rarely, allergic reaction or infection

How much does Plinest cost in Seoul?

₩200,000–₩500,000 (about US$150–375) — In Seoul, Plinest is usually priced higher than domestic PN brands because it is imported. Cost depends on the number of syringes and whether the eye area is included. Prices are estimates and change with promotions.

Why get Plinest in Korea?

Polynucleotide boosters are very common in Seoul, so doctors are experienced with this type of injection. Visitors can compare imported Plinest with Korean PN brands and often pay less than at home.

Frequently asked questions

How much does Plinest cost in Seoul?

Plinest usually costs about ₩200,000–₩500,000 per session in Seoul. Packages of 3 sessions often lower the price per visit.

Does Plinest hurt?

It causes mild stinging. Numbing cream is applied first, and most people find it manageable.

How many Plinest sessions do I need?

A typical course is 3 sessions about 2–3 weeks apart. Results usually last 4–6 months, then 1 maintenance session is common.

When can I fly after Plinest?

You can fly the same day or the next day. Small bumps may be visible for 1–2 days.

Is Plinest safe?

It is generally low risk when injected by a doctor. Tell the clinic if you have a fish allergy, as polynucleotides are often sourced from fish.

What is the difference between Plinest and Rejuran?

Both are polynucleotide skin boosters with similar goals. Plinest is made in Italy, while Rejuran is a Korean brand that is usually cheaper in Seoul.

Where to get it in Seoul

Foreigner-friendly clinics cluster around Gangnam, Sinsa–Apgujeong–Cheongdam and Myeongdong. Tap a number to zoom in, then tap a pin to ask the clinic on WhatsApp whether they offer this treatment and for a quote.